Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. Paclitaxel is approved for ovarian, breast and lung, bladder, prostate, melanoma, esophageal, and other types of solid tumor cancers as well as Kaposi's sarcoma. Paclitaxel is used as an antiproliferative agent for the prevention of restenosis (recurrent narrowing) of coronary stents; locally delivered to the wall of the coronary artery.
Docetaxel trihydrate is a clinically well-established anti-mitotic chemotherapy medication that works by interfering with cell division. Docetaxel is approved for treatment of locally advanced or metastatic breast cancer, head and neck cancer, gastric cancer, hormone-refractory prostate cancer and non small-cell lung cancer. Docetaxel can be used as a single agent or in combination with other chemotherapeutic drugs as indicated depending on specific cancer type and stage.
Ifosfamide is a nitrogen mustard alkylating agent used in the treatment of cancer. It is a white powder which, when prepared for use in chemotherapy. Ifosfamide is often used in conjunction with mesna to avoid internal bleeding in the patient, in particular hemorrhagic cystitis. It is given as a treatment for a variety of cancers, including Testicular cancer, Breast cancer, Lymphoma (Hodgkin's and non-Hodgkin's), Soft tissue sarcoma , Osteogenic sarcoma (bone cancer), Lung cancer, Cervical cancer and Ovarian cancer.
Etoposide is a cytotoxic anticancer drug which belongs to the topoisomerase inhibitor drug class. Etoposide is used as a form of chemotherapy for cancers such as Kaposi’s sarcoma, Ewing's sarcoma, lung cancer, testicular cancer, lymphoma, nonlymphocytic leukemia, and glioblastoma multiforme. It is often given in combination with other drugs (such as bleomycin in treating testicular cancer).
Cisplatin is a chemotherapy drug. It was the first member of a class of platinum-containing anti-cancer drugs. Cisplatin is administered intravenously as short-term infusion in normal saline for treatment of solid malignancies. It is used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas, and germ cell tumors.
Carboplatin is a chemotherapy drug used against some forms of cancer (mainly ovarian carcinoma, lung, head and neck cancers as well as endometrial, esophageal, bladder, breast and cervical; central nervous system or germ cell tumors; osteogenic sarcoma, and as preparation for a stem cell or bone marrow transplant.
Oxaliplatin is a platinum-based antineoplastic agent used in cancer chemotherapy.Oxaliplatin is used for treatment of colorectal cancer and in combination with folinic acid and 5-fluorouracil.
Satraplatin is a platinum-based antineoplastic agent for treatment of patients with advanced prostate cancer who have failed previous chemotherapy. Satraplatin is the first orally active platinum-based chemotherapeutic drug.
Picoplatin is a platinum-based antineoplastic agent for the treatment of patients with solid tumors.Picoplatin demonstrated activity in a variety of solid tumors, including lung, ovarian, colorectal and hormone-refractory prostate cancer.
Letrozole is an oral non-steroidal aromatase inhibitor for the treatment of hormonally-responsive breast cancer after surgery, Letrozole is sometimes used as a treatment for gynecomastia.